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Pneumococcal conjugate vaccines for preventing acute otitis media in children.


ABSTRACT:

SUBMITTER: Fortanier AC 

PROVIDER: S-EPMC6537667 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Pneumococcal conjugate vaccines for preventing acute otitis media in children.

Fortanier Alexandre C AC   Venekamp Roderick P RP   Boonacker Chantal Wb CW   Hak Eelko E   Schilder Anne Gm AG   Sanders Elisabeth Am EA   Damoiseaux Roger Amj RA  

The Cochrane database of systematic reviews 20190528


<h4>Background</h4>Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post-PCV era report a shift in causative otopathogens towards non-vaccine serotypes and other bacteria. This updated Cochrane Review was fir  ...[more]

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