Ontology highlight
ABSTRACT:
SUBMITTER: de Sevaux JL
PROVIDER: S-EPMC8096893 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
de Sévaux Joline Lh JL Venekamp Roderick P RP Lutje Vittoria V Hak Eelko E Schilder Anne Gm AG Sanders Elisabeth Am EA Damoiseaux Roger Amj RA
The Cochrane database of systematic reviews 20201124
<h4>Background</h4>Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from the middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post-PCV era report a shift in causative otopathogens towards non-vaccine serotypes and other bacteria. This updated Cochrane Review was ...[more]