Ontology highlight
ABSTRACT:
SUBMITTER: Sugihara Y
PROVIDER: S-EPMC6538158 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
PloS one 20190528 5
Recently, we showed that imidazole dipeptide such as carnosine contained abundantly in chicken breast meat improves brain function in a double-blind randomized controlled trial. However, the underlying molecular mechanisms remain unknown. Here, we investigated whether carnosine activates intestinal epithelial cells and induces the secretion of factors that activate brain function. We focused on exosomes derived from intestinal epithelial cells as mediators of brain-gut interaction. Results showe ...[more]