Ontology highlight
ABSTRACT:
SUBMITTER: Niklaus L
PROVIDER: S-EPMC6538699 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Niklaus L L Agop-Nersesian C C Schmuckli-Maurer J J Wacker R R Grünig V V Heussler V T VT
Scientific reports 20190528 1
Liver stage Plasmodium parasites reside in a parasitophorous vacuole (PV) that associates with lysosomes. It has previously been shown that these organelles can have beneficial as well as harmful effects on the parasite. Yet it is not clear how the association of lysosomes with the parasite is controlled and how interactions with these organelles lead to the antagonistic outcomes. In this study we used advanced imaging techniques to characterize lysosomal interactions with the PV. In host cells ...[more]