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The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019.

ABSTRACT: After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains.

SUBMITTER: Yu D 

PROVIDER: S-EPMC6540644 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019.

Yu Deshan D   Xiang Guofeng G   Zhu Wenfei W   Lei Xia X   Li Baodi B   Meng Yao Y   Yang Lei L   Jiao Hongyan H   Li Xiyan X   Huang Weijuan W   Wei Hejiang H   Zhang Yanping Y   Hai Yan Y   Zhang Hui H   Yue Hua H   Zou Shumei S   Zhao Xiang X   Li Chao C   Ao Deng D   Zhang Ye Y   Tan Minju M   Liu Jia J   Zhang Xuemei X   Gao George F GF   Meng Lei L   Wang Dayan D  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20190501 21

After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains. ...[more]

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