Ontology highlight
ABSTRACT:
SUBMITTER: Gil N
PROVIDER: S-EPMC6542670 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Cell systems 20181114 5
Active enhancers in mammals produce enhancer RNAs (eRNAs) that are bidirectionally transcribed, unspliced, and unstable. Enhancer regions are also enriched with long noncoding RNA (lncRNA) transcripts, which are typically spliced and substantially more stable. In order to explore the relationship between these two classes of RNAs, we analyzed DNase hypersensitive sites with evidence of bidirectional transcription, which we termed eRNA-producing centers (EPCs). EPCs found very close to transcript ...[more]