Ontology highlight
ABSTRACT:
SUBMITTER: Hartlieb M
PROVIDER: S-EPMC6544120 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Hartlieb Matthias M Catrouillet Sylvain S Kuroki Agnès A Sanchez-Cano Carlos C Peltier Raoul R Perrier Sébastien S
Chemical science 20190418 21
Cyclic peptide nanotubes (CPNT) consisting of an even number of amino acids with an alternating chirality are highly interesting materials in a biomedical context due to their ability to insert themselves into cellular membranes. However, unwanted unspecific interactions between CPNT and non-targeted cell membranes are a major drawback. To solve this issue we have synthetized a series of CPNT-polymer conjugates with a cleavable covalent connection between macromolecule and peptide. As a result, ...[more]