Regulation of microRNA function in animals.
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ABSTRACT:
SUBMITTER: Gebert LFR
PROVIDER: S-EPMC6546304 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Regulation of microRNA function in animals.
Gebert Luca F R LFR MacRae Ian J IJ
Nature reviews. Molecular cell biology 20190101 1
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as key regulators of biological processes in animals. These small RNAs form complex networks that regulate cell differentiation, development and homeostasis. Deregulation of miRNA function is associated with an increasing number of human diseases, particularly cancer. Recent discoveries have expanded our understanding of the control of miRNA function. Here, we review the mechanisms that modulate miRNA activity, sta ...[more]
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