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ABSTRACT: Objectives
To investigate survival among elderly residents of Swedish nursing homes (NHs), with specific focus on those with two or more signs of Lewy body dementia (LBD).Design
Prospective observational study.Setting
NHs in Malmö, the third largest city in Sweden.Participants
The study population was older adults (aged ?65 years) living in the 40 NHs in Malmö. Clinical data were collected with a customised questionnaire assessing core clinical LBD signs. Patients were categorised based on 0-1 or 2-4 LBD signs. The head nurse at each NH collected the study data: LBD questionnaires, electronic medication lists and electronic medical records from 2012 to 2013.Main outcome measures
80-month mortality.Results
Five hundred and fifty-eight (96%) of the residents were deceased at follow-up; among these, mean (95%?CI) overall survival time was 29 (28-31) months. Mean survival differed between the LBD groups; those with 0-1 LBD signs lived 8?months longer than those with 2-4 LBD signs. Mortality risk for residents in the LBD 2-4 group was also significantly higher. HR adjusted for age and sex was HR (95%?CI) 1.60 (1.30 to 1.97). Mortality risk was also significantly higher in residents with signs of fluctuating cognition 1.36 (1.15 to 1.62), rapid eye movement sleep behaviour disorder 1.49 (1.11 to 1.98), balance problems 1.36 (1.14 to 1.61) or rigidity 1.41 (1.18 to 1.68).Conclusions
This large, longitudinal study shows the important survival effects of identifying and diagnosing older adults NH residents who have two or more LBD signs.
SUBMITTER: Zahirovic I
PROVIDER: S-EPMC6549645 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Zahirovic Iris I Torisson Gustav G Wattmo Carina C Londos Elisabet E
BMJ open 20190530 5
<h4>Objectives</h4>To investigate survival among elderly residents of Swedish nursing homes (NHs), with specific focus on those with two or more signs of Lewy body dementia (LBD).<h4>Design</h4>Prospective observational study.<h4>Setting</h4>NHs in Malmö, the third largest city in Sweden.<h4>Participants</h4>The study population was older adults (aged ≥65 years) living in the 40 NHs in Malmö. Clinical data were collected with a customised questionnaire assessing core clinical LBD signs. Patients ...[more]