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Optically Responsive, Smart Anti-Bacterial Coatings via the Photofluidization of Azobenzenes.

ABSTRACT: Antibacterial strategies sans antibiotic drugs have recently garnered much interest as a mechanism by which to inhibit biofilm formation and growth on surfaces due to the rise of antibiotic-resistant bacteria. Based on the photofluidization of azobenzenes, we demonstrate for the first time the ability achieve up to a 4 log reduction in bacterial biofilms by opto-mechanically activating the disruption and dispersion of biofilms. This unique strategy with which to enable biofilm removal offers a novel paradigm with which to combat antibiotic resistance.

SUBMITTER: Kehe GM

PROVIDER: S-EPMC6552654 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Optically Responsive, Smart Anti-Bacterial Coatings via the Photofluidization of Azobenzenes.

Kehe Gannon M GM Mori Dylan I DI Schurr Michael J MJ Nair Devatha P DP

ACS applied materials & interfaces 20190104 2

Antibacterial strategies sans antibiotic drugs have recently garnered much interest as a mechanism by which to inhibit biofilm formation and growth on surfaces due to the rise of antibiotic-resistant bacteria. Based on the photofluidization of azobenzenes, we demonstrate for the first time the ability achieve up to a 4 log reduction in bacterial biofilms by opto-mechanically activating the disruption and dispersion of biofilms. This unique strategy with which to enable biofilm removal offers a n ...[more]

PMID: 30605328

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