Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC6553855 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Liu Jianghong J Liu Shengshuo S Deng Xiaoyan X Rao Jiaoyu J Huang Kaiyuan K Xu Gengrui G Wang Xiaokang X
PloS one 20190606 6
Non-small cell lung cancer (NSCLC) is the most common cancer worldwide. MicroRNAs have been shown to be correlated with biological processes of various tumors. In this study, we observed that the expression of miR-582-5p was lower in NSCLC tissues than that in para-carcinoma tissues. Ectopic expression of miR-582-5p significantly inhibited NCI-H358 cell proliferation and invasion. Knockdown of miR-582-5p showed the opposite results, with cell growth rate and the invasive capacity of PC-9 cells e ...[more]