Ontology highlight
ABSTRACT:
SUBMITTER: Du Pont V
PROVIDER: S-EPMC6556400 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Current opinion in virology 20190210
Rabies virus (RABV) constitutes a major social and economic burden associated with 60 000 deaths annually worldwide. Although pre-exposure and post-exposure treatment options are available, they are efficacious only when initiated before the onset of clinical symptoms. Aggravating the problem, the current RABV vaccine does not cross-protect against the emerging zoonotic phylogroup II lyssaviruses. A requirement for an uninterrupted cold chain and high cost of the immunoglobulin component of rabi ...[more]