Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC6556600 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Li Xiaoxue X Zhang Yongjing Y Chai Xiaoshan X Zhou Shuhua S Zhang Hongbo H He Jie J Zhou Ruiqiong R Cai Lan L Chen Lin L Tao Guangshi G
American journal of cancer research 20190501 5
The transcription factor MEF2 promotes survival in various cell types and a number of studies indicate that abnormal regulation of MEF2 is linked to oncogenicity in several carcinomas. We have found that MEF2D, a member of the MEF2 family, is upregulated in Ovarian Cancer (OC). Immunohistochemistry analysis of tumor sections of 402 OC patients revealed that MEF2D is significantly elevated at the protein level. We have also found that the expression level of MEF2D is associated with cisplatin-res ...[more]