Ontology highlight
ABSTRACT:
SUBMITTER: Ai G
PROVIDER: S-EPMC6556631 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
American journal of translational research 20190515 5
microRNAs play important roles in proliferation and differentiation of stem cells, but mechanisms by which microRNAs regulate osteogenic or adipogenic differentiation of adipose stem cells (ASCs) are still poorly understood. In the present study, results showed up-regulation of microRNA-196a was able to promote the osteogenic differentiation of ACSs, but down-regulation of microRNA-196a induced adipogenic differentiation. Further investigation indicated microRNA-196a could regulate Wnt signaling ...[more]