Ontology highlight
ABSTRACT:
SUBMITTER: Alatrash G
PROVIDER: S-EPMC6557700 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Alatrash Gheath G Kidwell Kelly M KM Thall Peter F PF Di Stasi Antonio A Chen Julianne J Zope Madhushree M Crain Alyssa K AK Champlin Richard E RE Popat Uday U Shpall Elizabeth J EJ Jones Roy B RB Andersson Borje S BS
Bone marrow transplantation 20181210 8
Conditioning regimens contribute significantly to outcomes following allogeneic stem cell transplantation (allo-SCT). Reduced-intensity conditioning (RIC) regimens provide lower toxicity at the cost of reduced efficacy compared with myeloablative conditioning (MAC) regimens. However, because pre-transplant prognostic variables often determine the conditioning regimen, studies of RIC vs. MAC have been inconclusive. We present a retrospective analysis of 242 acute myeloid leukemia (AML) or myelody ...[more]