Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki Y
PROVIDER: S-EPMC6560220 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Suzuki Yuka Y Bilir Şükriye Ş Hatano Yu Y Fukuda Tatsuhito T Mashiko Daisuke D Kobayashi Shouhei S Hiraoka Yasushi Y Haraguchi Tokuko T Yamagata Kazuo K
Scientific reports 20190611 1
Reformation of a functional nucleus at the end of mitosis is crucial for normal cellular activity. Reconstitution approaches using artificial beads in frog egg extracts have clarified the molecules required for nuclear formation in vitro. However, the spatiotemporal regulation of these components, which is required for the formation of a functional nucleus in living embryos, remains unknown. Here we demonstrate that exogenous DNA introduced in the form of DNA-conjugated beads induces the assembl ...[more]