Ontology highlight
ABSTRACT:
SUBMITTER: Gordon WE
PROVIDER: S-EPMC6561644 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Gordon Wei E WE Espinoza Jose A JA Leerberg Dena M DM Yelon Deborah D Hamdoun Amro A
Aquatic toxicology (Amsterdam, Netherlands) 20190425
Ionocytes are specialized cells in the epidermis of embryonic zebrafish (Danio rerio) that play important roles in ion homeostasis and have functional similarities to mammalian renal cells. Here, we examined whether these cells might also share another functional similarity with renal cells, which is the presence of efflux transporter activities useful for elimination of toxic small molecules. Xenobiotic transporters (XTs), including the ATP-Binding Cassette (ABC) family, are a major defense mec ...[more]