Ontology highlight
ABSTRACT:
SUBMITTER: Yang XH
PROVIDER: S-EPMC6563821 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20190208 7
In this Article, we expand upon the catalytic hydrothiolation of 1,3-dienes to afford either allylic or homoallylic sulfides with high regiocontrol. Mechanistic studies support a pathway in which regioselectivity is dictated by the choice of counterion associated with the Rh center. Non-coordinating counterions, such as SbF<sub>6</sub><sup>-</sup>, allow for η<sup>4</sup>-diene coordination to Rh complexes and result in allylic sulfides. In contrast, coordinating counterions, such as Cl<sup>-</s ...[more]