Catalytic Hydrothiolation: Regio- and Enantioselective Coupling of Thiols and Dienes.

ABSTRACT: We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secondary or tertiary allylic sulfides can be generated from the selective addition of a thiol to the more substituted double bond of a diene. The catalyst tolerates a wide range of functional groups, and the loading can be as low as 0.1 mol %.

SUBMITTER: Yang XH 

PROVIDER: S-EPMC6563822 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature