Ontology highlight
ABSTRACT:
SUBMITTER: Zheng Y
PROVIDER: S-EPMC6564687 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Zheng Yang Y Zhang Junqi J Cheng Xinpeng X Xu Xinfang X Zhang Liming L
Angewandte Chemie (International ed. in English) 20190318 16
Gold-catalyzed oxidations of alkynes by N-oxides offer direct access to reactive α-oxo gold carbene intermediates from benign and readily available alkynes instead of hazardous diazo carbonyl compounds. Despite various versatile synthetic methods developed based on this strategy, one of the hallmarks of α-oxo carbene/carbenoid chemistry, that is, the Wolff rearrangement, has not been realized in this context. This study discloses the first examples that show the Wolff rearrangement can be readil ...[more]