Unknown

Dataset Information

0

Alkynes as equivalents of alpha-diazo ketones in generating alpha-oxo metal carbenes: a gold-catalyzed expedient synthesis of dihydrofuran-3-ones.

ABSTRACT: An expedient and reliable method for accessing reactive alpha-oxo gold carbenes via gold-catalyzed intermolecular oxidation of terminal alkynes has been developed. Significantly, this method offers a safe and economical alternative to the strategies based on diazo substrates. Its synthetic potential is demonstrated by expedient preparation of dihydrofuran-3-ones containing a broad range of functional groups.

SUBMITTER: Ye L 

PROVIDER: S-EPMC2847863 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Alkynes as equivalents of alpha-diazo ketones in generating alpha-oxo metal carbenes: a gold-catalyzed expedient synthesis of dihydrofuran-3-ones.

Ye Longwu L   Cui Li L   Zhang Guozhu G   Zhang Liming L  

Journal of the American Chemical Society 20100301 10

An expedient and reliable method for accessing reactive alpha-oxo gold carbenes via gold-catalyzed intermolecular oxidation of terminal alkynes has been developed. Significantly, this method offers a safe and economical alternative to the strategies based on diazo substrates. Its synthetic potential is demonstrated by expedient preparation of dihydrofuran-3-ones containing a broad range of functional groups. ...[more]

Similar Datasets

Unknown Rhodium-catalyzed intramolecular C-H insertion of alpha-aryl-alpha-diazo ketones.
| S-EPMC3248813 | biostudies-literature
Unknown A non-diazo approach to α-oxo gold carbenes via gold-catalyzed alkyne oxidation.
| S-EPMC3983127 | biostudies-other
Unknown Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines.
| S-EPMC7089982 | biostudies-literature
Unknown Two Copper-Carbenes from One Diazo Compound.
| S-EPMC8603358 | biostudies-literature
Unknown Synthesis of α-heterosubstituted ketones through sulfur mediated difunctionalization of internal alkynes.
| S-EPMC6524669 | biostudies-other
Unknown Synthesis of novel 2H,5H-Dihydrofuran-3-yl Ketones via ISNC reactions.
| S-EPMC2782825 | biostudies-literature
Unknown Decarboxylative benzylations of alkynes and ketones.
| S-EPMC2923406 | biostudies-literature
Unknown Preparation of α-Perfluoroalkyl Ketones from α,β-Unsaturated Ketones via Formal Hydroperfluoroalkylation.
| S-EPMC7901661 | biostudies-literature
Unknown Ketones and aldehydes as alkyl radical equivalents for C─H functionalization of heteroarenes.
| S-EPMC6788867 | biostudies-literature
Unknown Generation of rhodium(I) carbenes from ynamides and their reactions with alkynes and alkenes.
| S-EPMC3884031 | biostudies-literature