Ontology highlight
ABSTRACT:
SUBMITTER: Barral-Arca R
PROVIDER: S-EPMC6573782 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Barral-Arca Ruth R Pardo-Seco Jacobo J Bello Xabi X Martinón-Torres Federico F Salas Antonio A
RNA (New York, N.Y.) 20190422 7
There is a growing body of evidence suggesting that patterns of gene expression vary within and between human populations. However, the impact of this variation in human diseases has been poorly explored, in part owing to the lack of a standardized protocol to estimate biogeographical ancestry from gene expression studies. Here we examine several studies that provide new solid evidence indicating that the ancestral background of individuals impacts gene expression patterns. Next, we test a proce ...[more]