Ontology highlight
ABSTRACT:
SUBMITTER: Park GK
PROVIDER: S-EPMC6574216 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Park G Kate GK Lee Jeong Heon JH Levitz Andrew A El Fakhri Georges G Hwang Nathaniel S NS Henary Maged M Choi Hak Soo HS
Advanced materials (Deerfield Beach, Fla.) 20190210 14
Longitudinal tracking of living cells is crucial to understanding the mechanism of action and toxicity of cell-based therapeutics. To quantify the presence of administered cells in the host tissue without sacrifice of animals, labeling of the target cells with a nontoxic and stable contrast agent is a prerequisite. However, such long-term live cell tracking is currently limited by the lack of fluorophores with steady optical and physicochemical properties in the near-infrared (NIR) window. Herei ...[more]