Ontology highlight
ABSTRACT:
SUBMITTER: Piccirillo AR
PROVIDER: S-EPMC6581627 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20190524 1
Access to nutrients is critical for an effective T cell immune response to infection. Although transporters for sugars and amino acids have previously been described in the context of the CD8<sup>+</sup> T cell immune response, the active transport of exogenous fatty acids has remained enigmatic. In this study, we discovered that the sodium-dependent lysophosphatidylcholine (LPC) transporter major facilitator superfamily domain containing 2A (MFSD2A) is upregulated on activated CD8<sup>+</sup> T ...[more]