Ontology highlight
ABSTRACT:
SUBMITTER: Shu T
PROVIDER: S-EPMC6582406 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Shu Ting T Gan Tianyu T Bai Peng P Wang Xiaotong X Qian Qi Q Zhou Hui H Cheng Qi Q Qiu Yang Y Yin Lei L Zhong Jin J Zhou Xi X
Nucleic acids research 20190601 11
Ebola virus (EBOV) is a non-segmented, negative-sense RNA virus (NNSV) in the family Filoviridae, and is recognized as one of the most lethal pathogens in the planet. For RNA viruses, cellular or virus-encoded RNA helicases play pivotal roles in viral life cycles by remodelling viral RNA structures and/or unwinding viral dsRNA produced during replication. However, no helicase or helicase-like activity has ever been found to associate with any NNSV-encoded proteins, and it is unknown whether the ...[more]