Ontology highlight
ABSTRACT:
SUBMITTER: Chu T
PROVIDER: S-EPMC6584046 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Chu Tinyi T Wang Zhong Z Chou Shao-Pei SP Danko Charles G CG
Current protocols in bioinformatics 20181227 1
Transcription is a chromatin mark that can be used effectively to identify the location of active enhancers and promoters, collectively known as transcriptional regulatory elements (TREs). We recently introduced dREG, a tool for the identification of TREs using run-on and sequencing (RO-seq) assays, including global run-on and sequencing (GRO-seq), precision run-on and sequencing (PRO-seq), and chromatin run-on and sequencing (ChRO-seq). In this protocol, we present step-by-step instructions for ...[more]