Ontology highlight
ABSTRACT:
SUBMITTER: Kruger S
PROVIDER: S-EPMC6585101 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Kruger Stephan S Ilmer Matthias M Kobold Sebastian S Cadilha Bruno L BL Endres Stefan S Ormanns Steffen S Schuebbe Gesa G Renz Bernhard W BW D'Haese Jan G JG Schloesser Hans H Heinemann Volker V Subklewe Marion M Boeck Stefan S Werner Jens J von Bergwelt-Baildon Michael M
Journal of experimental & clinical cancer research : CR 20190619 1
Immunotherapy has become an established pillar of cancer treatment improving the prognosis of many patients with a broad variety of hematological and solid malignancies. The two main drivers behind this success are checkpoint inhibitors (CPIs) and chimeric antigen receptor (CAR) T cells. This review summarizes seminal findings from clinical and translational studies recently presented or published at important meetings or in top-tier journals, respectively. For checkpoint blockade, current studi ...[more]