Protein secondary structure analysis of dried blood serum using infrared spectroscopy to identify markers for colitis screening.
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ABSTRACT:
SUBMITTER: Titus J
PROVIDER: S-EPMC6587188 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
Protein secondary structure analysis of dried blood serum using infrared spectroscopy to identify markers for colitis screening.
Titus Jitto J Ghimire Hemendra H Viennois Emilie E Merlin Didier D Unil Perera A G AG
Journal of biophotonics 20170912 3
There remains a great need for diagnosis of inflammatory bowel disease, for which the current technique, colonoscopy, is costly and also has risks for complications. Attenuated total reflectance Fourier transform infrared spectroscopy is a new screening technique to evaluate colitis. Using second derivative spectral deconvolution of the absorbance spectra, a full set of spectral markers were identified based on statistical analysis. Using this method, Amide I group frequencies, (specifically, α- ...[more]
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