Ontology highlight
ABSTRACT:
SUBMITTER: Heidegger I
PROVIDER: S-EPMC6587703 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Heidegger Isabel I Pircher Andreas A Pichler Renate R
Frontiers in oncology 20190614
Renal cell cancer (RCC) is a highly vascularized and immunogenic tumor type. The inhibition of vessel formation by anti-angiogenic therapies, as well as the stimulation of the immune system by immunotherapy has revolutionized the therapeutic landscape of RCC in recent years. Nevertheless, both therapies are associated with therapy resistance due to a highly dynamic, adaptive and heterogeneous tumor microenvironment (TME). The aim of this short review article is to provide an overview of the comp ...[more]