Ontology highlight
ABSTRACT:
SUBMITTER: Buque A
PROVIDER: S-EPMC4938376 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Buqué Aitziber A Bloy Norma N Aranda Fernando F Cremer Isabelle I Eggermont Alexander A Fridman Wolf Hervé WH Fucikova Jitka J Galon Jérôme J Spisek Radek R Tartour Eric E Zitvogel Laurence L Kroemer Guido G Galluzzi Lorenzo L
Oncoimmunology 20160310 6
Progressing malignancies establish robust immunosuppressive networks that operate both systemically and locally. In particular, as tumors escape immunosurveillance, they recruit increasing amounts of myeloid and lymphoid cells that exert pronounced immunosuppressive effects. These cells not only prevent the natural recognition of growing neoplasms by the immune system, but also inhibit anticancer immune responses elicited by chemo-, radio- and immuno therapeutic interventions. Throughout the pas ...[more]