Ontology highlight
ABSTRACT:
SUBMITTER: Kim KS
PROVIDER: S-EPMC6588159 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Kim Kyoung Sub KS Kwag Dong Sup DS Hwang Hee Sook HS Lee Eun Seong ES Bae You Han YH
Molecular pharmaceutics 20180829 10
We provide immense insulin absorption from the gastrointestinal tract, combining apical sodium-dependent bile acid transporter-mediated intestinal uptake and the lymphatic transport pathway. This strategy has proven to employ chondroitin sulfate- g-taurocholic acid coated, insulin-loaded partially uncapped liposome (IPUL-CST) for type 1 diabetes mellitus (T1DM) treatment. The loading efficiency of insulin in IPUL-CST increased significantly from 33% to 75% via the partially uncapped liposome pre ...[more]