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A multinational observational study assessing insulin use: Understanding the determinants associated with progression of therapy.


ABSTRACT: AIMS:To describe global patterns of insulin treatment and to assess the impact of patient, provider, health system and economic influences on treatment decisions for patients with insulin-treated type 2 diabetes (T2D). METHODS:This prospective cohort study of insulin-treated patients with T2D was conducted across 18 countries categorized as high, upper-middle or lower-middle income regions. Information collected from patients included knowledge of diabetes, experiences and interactions with their healthcare provider. Physician information included specialty, practice size, availability of diabetes support services, volume of diabetes patients treated and time spent per patient. Physicians determined an individualized haemoglobin A1c (HbA1c) target for each patient by the start of the study. Changes in T2D therapies and HbA1c were recorded for 2?years. RESULTS:Complete treatment data were available for 2528 patients. Median age was 61?years and median duration of diabetes was 11.4?years. Changes to treatment regimen occurred in 90.0% of patients, but changes were less common in countries with a higher economic status (P?

SUBMITTER: Ray KK 

PROVIDER: S-EPMC6590265 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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A multinational observational study assessing insulin use: Understanding the determinants associated with progression of therapy.

Ray Kausik K KK   Ray Kausik K KK   Kendall David M DM   Zhao Zhenxiang Z   Peng Xiaomei X   Caballero A Enrique AE   Polonsky William H WH   Nordstrom Beth L BL   Fan Ludi L   Curtis Bradley H BH   Davies Melanie J MJ  

Diabetes, obesity & metabolism 20190124 5


<h4>Aims</h4>To describe global patterns of insulin treatment and to assess the impact of patient, provider, health system and economic influences on treatment decisions for patients with insulin-treated type 2 diabetes (T2D).<h4>Methods</h4>This prospective cohort study of insulin-treated patients with T2D was conducted across 18 countries categorized as high, upper-middle or lower-middle income regions. Information collected from patients included knowledge of diabetes, experiences and interac  ...[more]

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