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Vitamin D deficiency during pregnancy and its associated factors among third trimester Malaysian pregnant women.


ABSTRACT:

Background

Despite perennial sunshine, vitamin D deficiency is prevalent among Malaysians especially pregnant women. This study determines the vitamin D status and its associated factors among third trimester pregnant women attending government health clinics in Selangor and Kuala Lumpur, Malaysia.

Methods

Information on socio-demographic characteristics, obstetrical history, and sun exposure were obtained through face-to-face interviews. Vitamin D intake was assessed using a semi-quantitative food frequency questionnaire (FFQ). Serum 25-hydroxyvitamin D concentration was measured and classified as deficient (< 30 nmol/L), insufficient (30-50 nmol/L), and sufficient (? 50 nmol/L).

Results

Of the 535 pregnant women recruited, 42.6% were vitamin D deficient. They consumed an average of 8.7 ± 6.7 ?g of vitamin D daily. A total of 80.4% of the vitamin D were obtained from the food sources, while 19.6% were from dietary supplements. Fish and fish products showed the highest contribution to vitamin D intake (35.8%). The multivariable generalized linear mixed models, with clinic as a random effect, indicates that higher intake of vitamin D is associated with lower odds of vitamin D deficiency among pregnant women (OR = 0.96; 95% CI = 0.93-0.99). The odds of having vitamin D deficiency was reduced by 87% in non-Malays (OR = 0.14; 95% CI = 0.05-0.41) compared to Malays. No associations were found between age, educational level, monthly household income, work status, gravidity, parity, pre-pregnancy body mass index, total hours of sun exposure, total percentage of body surface area, and sun exposure index per day with vitamin D deficiency.

Conclusion

Vitamin D deficiency is prevalent among Malaysian pregnant women. Considering the possible adverse obstetric and fetal outcomes of vitamin D deficiency during pregnancy, future nutrition education should emphasise on vitamin D-fortified foods consumption among pregnant women by taking into consideration ethnic differences.

SUBMITTER: Woon FC 

PROVIDER: S-EPMC6590777 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Vitamin D deficiency during pregnancy and its associated factors among third trimester Malaysian pregnant women.

Woon Fui Chee FC   Chin Yit Siew YS   Ismail Intan Hakimah IH   Batterham Marijka M   Abdul Latiff Amir Hamzah AH   Gan Wan Ying WY   Appannah Geeta G   Mohammed Hussien Siti Huzaifah SH   Edi Muliana M   Tan Meng Lee ML   Chan Yoke Mun YM  

PloS one 20190624 6


<h4>Background</h4>Despite perennial sunshine, vitamin D deficiency is prevalent among Malaysians especially pregnant women. This study determines the vitamin D status and its associated factors among third trimester pregnant women attending government health clinics in Selangor and Kuala Lumpur, Malaysia.<h4>Methods</h4>Information on socio-demographic characteristics, obstetrical history, and sun exposure were obtained through face-to-face interviews. Vitamin D intake was assessed using a semi  ...[more]

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