Ontology highlight
ABSTRACT:
SUBMITTER: Ariyoshi K
PROVIDER: S-EPMC6591216 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Ariyoshi Kentaro K Miura Tomisato T Kasai Kosuke K Fujishima Yohei Y Nakata Akifumi A Yoshida Mitsuaki M
Scientific reports 20190624 1
Exosome-like vesicles (ELV) are involved in mediating radiation-induced bystander effect (RIBE). Here, we used ELV from control cell conditioned medium (CCCM) and from 4 Gy of X-ray irradiated cell conditioned medium (ICCM), which has been used to culture normal human fibroblast cells to examine the possibility of ELV mediating RIBE signals. We investigated whether ELV from 4 Gy irradiated mouse serum mediate RIBE signals. Induction of DNA damage was observed in cells that were treated with ICCM ...[more]