Ontology highlight
ABSTRACT:
SUBMITTER: Drake MG
PROVIDER: S-EPMC6592848 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Science translational medicine 20180901 457
In asthma, airway nerve dysfunction leads to excessive bronchoconstriction and cough. It is well established that eosinophils alter nerve function and that airway eosinophilia is present in 50 to 60% of asthmatics. However, the effects of eosinophils on airway nerve structure have not been established. We tested whether eosinophils alter airway nerve structure and measured the physiological consequences of those changes. Our results in humans with and without eosinophilic asthma showed that airw ...[more]