Immune senescence and immune activation in elderly colorectal cancer patients.
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ABSTRACT:
SUBMITTER: Giunco S
PROVIDER: S-EPMC6594805 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Immune senescence and immune activation in elderly colorectal cancer patients.
Giunco Silvia S Petrara Maria Raffaella MR Bergamo Francesca F Del Bianco Paola P Zanchetta Marisa M Carmona Francesco F Zagonel Vittorina V De Rossi Anita A Lonardi Sara S
Aging 20190601 11
In our previous study, we found that low thymic output and short telomere length were associated with a higher risk of tumor in elderly cancer patients. Here, we aimed to examine in depth the impact of immunological and biological senescence and immune activation on disease outcome in elderly patients with colorectal cancer (CRC).Peripheral blood samples from 81 CRC patients were studied for immune activation, immune senescence and recent thymic emigrant(RTE) CD4 and CD8 cells by flow cytometry. ...[more]
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