Dataset Information

Draft Whole-Genome Sequences of 16 Campylobacter jejuni Isolates Obtained from Wild Birds.

ABSTRACT: The draft genome sequences of 16 Campylobacter jejuni isolates obtained from wild birds are presented in this study. These genomes provide insights into the genetic features of C. jejuni isolates from wild birds, which are considered common hosts of this microorganism but have scarcely been investigated to date.

SUBMITTER: Carraro L

PROVIDER: S-EPMC6597683 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Draft Whole-Genome Sequences of 16 Campylobacter jejuni Isolates Obtained from Wild Birds.

Carraro Lisa L Marotta Francesca F Janowicz Anna A Patavino Claudio C Piccirillo Alessandra A

Microbiology resource announcements 20190627 26

The draft genome sequences of 16 <i>Campylobacter jejuni</i> isolates obtained from wild birds are presented in this study. These genomes provide insights into the genetic features of <i>C. jejuni</i> isolates from wild birds, which are considered common hosts of this microorganism but have scarcely been investigated to date. ...[more]

PMID: 31248999

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Project description:Poultry are considered a major reservoir and source of human campylobacteriosis, but the roles of environmental reservoirs, including wild birds, have not been assessed in depth. In this study, we isolated and characterized Campylobacter jejuni from western jackdaws (n = 91, 43%), mallard ducks (n = 82, 76%), and pheasants (n = 9, 9%). Most of the western jackdaw and mallard duck C. jejuni isolates represented multilocus sequence typing (MLST) sequence types (STs) that diverged from those previously isolated from human patients and various animal species, whereas all pheasant isolates represented ST-19, a common ST among human patients and other hosts worldwide. Whole-genome MLST revealed that mallard duck ST-2314 and pheasant ST-19 isolates represented bacterial clones that were genetically highly similar to human isolates detected previously. Further analyses revealed that in addition to a divergent ClonalFrame genealogy, certain genomic characteristics of the western jackdaw C. jejuni isolates, e.g., a novel cdtABC gene cluster and the type VI secretion system (T6SS), may affect their host specificity and virulence. Game birds may thus pose a risk for acquiring campylobacteriosis; therefore, hygienic measures during slaughter and meat handling warrant special attention.IMPORTANCE The roles of environmental reservoirs, including wild birds, in the molecular epidemiology of Campylobacter jejuni have not been assessed in depth. Our results showed that game birds may pose a risk for acquiring campylobacteriosis, because they had C. jejuni genomotypes highly similar to human isolates detected previously. Therefore, hygienic measures during slaughter and meat handling warrant special attention. On the contrary, a unique phylogeny was revealed for the western jackdaw isolates, and certain genomic characteristics identified among these isolates are hypothesized to affect their host specificity and virulence. Comparative genomics within sequence types (STs), using whole-genome multilocus sequence typing (wgMLST), and phylogenomics are efficient methods to analyze the genomic relationships of C. jejuni isolates.

Dataset Information

Draft Whole-Genome Sequences of 16 Campylobacter jejuni Isolates Obtained from Wild Birds.

Publications

Draft Whole-Genome Sequences of 16 Campylobacter jejuni Isolates Obtained from Wild Birds.

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