Weight loss changed gait kinematics in individuals with obesity and knee pain.

ABSTRACT: BACKGROUND:Obesity is a mechanical risk factor for osteoarthritis. In individuals with obesity, knee joint pain is prevalent. Weight loss reduces joint loads, and therefore potentially delays disease progression; however, how the knee joint responds to weight loss in individuals with obesity and knee pain is not clear. RESEARCH QUESTION:To assess the effect of weight loss on knee joint kinematics during gait in individuals with obesity and knee pain. METHODS:We recruited individuals with obesity (BMI???35) and knee pain who were participating in a weight loss program which included bariatric surgery or medical management. At baseline and 1 year follow-up, participants walked on a treadmill, and their knee joint kinematics were assessed using a dual-fluoroscopic imaging system and subject-specific magnetic resonance imaging knee joint models. Gait changes were represented by change in range of tibiofemoral motion, i.e., excursions in flexion-extension, adduction-abduction, internal-external rotation, anterior-posterior translation, medial-lateral translation, and superior-inferior translation during gait. RESULTS:Twelve individuals with obesity and knee pain completed the gait analysis at baseline and 1?year follow-up. Participants lost on average 10.4% (standard deviation: 17.2%) of their baseline body weight. Reduction in body weight was associated with increased range of flexion-extension (r = -0.75, p?

SUBMITTER: Li JS 

PROVIDER: S-EPMC6599530 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature