Ontology highlight
ABSTRACT:
SUBMITTER: Singh G
PROVIDER: S-EPMC6602504 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Singh Gurdeep G Inoue Asuka A Gutkind J Silvio JS Russell Robert B RB Russell Robert B RB Raimondi Francesco F
Nucleic acids research 20190701 W1
G-protein coupled receptors (GPCRs) control multiple physiological states by transducing a multitude of extracellular stimuli into the cell via coupling to intra-cellular heterotrimeric G-proteins. Deciphering which G-proteins couple to each of the hundreds of GPCRs present in a typical eukaryotic organism is therefore critical to understand signalling. Here, we present PRECOG (precog.russelllab.org): a web-server for predicting GPCR coupling, which allows users to: (i) predict coupling probabil ...[more]