Phosphorylation of G3BP1-S149 does not influence stress granule assembly.
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ABSTRACT:
SUBMITTER: Panas MD
PROVIDER: S-EPMC6605800 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
Phosphorylation of G3BP1-S149 does not influence stress granule assembly.
Panas Marc D MD Kedersha Nancy N Schulte Tim T Branca Rui M RM Ivanov Pavel P Anderson Paul P
The Journal of cell biology 20190606 7
Tourrière et al. (2013. <i>J. Cell Biol.</i> https://doi.org/10.1083/jcb.200212128) reported that G3BP1-S149 dephosphorylation promotes stress granule formation. We show that constructs used to establish this conclusion contain additional mutations causing these phenotypes, and that S149 phosphorylation status does not change upon stress. ...[more]
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