Emerging immunotherapies for autoimmune kidney disease.
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ABSTRACT:
SUBMITTER: Foster MH
PROVIDER: S-EPMC6605834 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Emerging immunotherapies for autoimmune kidney disease.
Foster Mary Helen MH Ord Jeffrey Robinson JR
Human vaccines & immunotherapeutics 20190116 4
Autoimmunity is a leading cause of chronic kidney disease and loss of native and transplanted kidneys. Conventional immunosuppressive therapies can be effective but are non-specific, noncurative, and risk serious side effects such as life-threatening infection and cancer. Novel therapies and targeted interventions are urgently needed. In this brief review we explore diverse strategies currently in development and under consideration to interrupt underlying disease mechanisms in immune-mediated r ...[more]
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