Ontology highlight
ABSTRACT:
SUBMITTER: Chen S
PROVIDER: S-EPMC6608053 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Chen Shuhua S Hoffman Rosemary A RA Scott Melanie M Manson Joanna J Loughran Patricia P Ramadan Mostafa M Demetris Anthony J AJ Billiar Timothy R TR
Journal of leukocyte biology 20170517 1
Various cell populations expressing NK1.1 contribute to innate host defense and systemic inflammatory responses, but their role in hemorrhagic shock and trauma remains uncertain. NK1.1<sup>+</sup> cells were depleted by i.p. administration of anti-NK1.1 (or isotype control) on two consecutive days, followed by hemorrhagic shock with resuscitation and peripheral tissue trauma (HS/T). The plasma levels of IL-6, MCP-1, alanine transaminase (ALT), and aspartate aminotransferase (AST) were measured a ...[more]