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Hepatitis E Infection in HIV-Infected Patients.

ABSTRACT: Background:The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income countries, HEV infection is considered a zoonotic disease that is linked to the consumption of contaminated food. Although a high proportion of cases have self-limiting asymptomatic or subclinical infections, immunosuppression may modify the pathogenesis and clinical impact of this emerging disease. Results and Discussion:Here, we review the current knowledge about the epidemiology, diagnosis, clinical manifestations, management and prevention of HEV infection in HIV-infected subjects. Conclusions:Despite the increasing knowledge about the pathogenesis, epidemiology and clinical impact of HEV infection, several major factors are faced by HIV-infected patients, including treatment recommendations, immunization and risk practices.

SUBMITTER: Rivero-Juarez A

PROVIDER: S-EPMC6608679 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Hepatitis E Infection in HIV-Infected Patients.

Rivero-Juarez Antonio A Lopez-Lopez Pedro P Frias Mario M Rivero Antonio A

Frontiers in microbiology 20190626

<h4>Background</h4>The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income countries, HEV infection is considered a zoonotic disease that is linked to the consumption of contaminated food. Although a high proportion of cases have self-limiting as ...[more]

PMID: 31297100

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