Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC6610041 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Li Shimiao S Chai Yi Y Ding Yanbao Y Yuan Tinghao T Wu Changwen C Huang Changwen C
Oncology reports 20190528 2
Chromodomain helicase/ATPase DNA‑binding protein 1‑like gene (CHD1L) is a new oncogene which has been confirmed to be crucial to the progression of many solid tumors. In the present study, the expression of CHD1L was found to be upregulated in intrahepatic cholangiocarcinoma (ICC), which was significantly associated with histological differentiation (P=0.011), vascular invasion (P=0.002), lymph node metastasis (P=0.008) and TNM stage (P=0.001). Kaplan‑Meier survival analysis revealed that ICC pa ...[more]