Ontology highlight
ABSTRACT:
SUBMITTER: Yang XW
PROVIDER: S-EPMC5352354 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Yang Xin-Wei XW Li Liang L Hou Guo-Jun GJ Yan Xin-Zhou XZ Xu Qin-Guo QG Chen Lei L Zhang Bao-Hua BH Shen Feng F
Oncotarget 20170101 5
Signal transducer and activator of transcription 3 (STAT3) promotes tumor progression in many types of cancer. In this study, we analyzed the prognostic value of this marker in human intrahepatic cholangiocarcinoma (ICC). Using real-time PCR, western blot and immunohistochemistry assays, we found that STAT3 is overexpressed in ICC patients. STAT3 expression correlated with several clinicopathological features, including tumor size, pathological satellite, vascular invasion, undifferentiated-type ...[more]