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ABSTRACT:
SUBMITTER: Aupic C
PROVIDER: S-EPMC6611065 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Aupic Clara C Abdou Mohamed Amel A Figliola Carlotta C Nava Paola P Tuccio Béatrice B Chouraqui Gaëlle G Parrain Jean-Luc JL Chuzel Olivier O
Chemical science 20190524 26
Stereogenic main group elements are clearly generating interest in the enantioselective catalysis field. Surprisingly, while chiral organoboron reagents are very useful in stereoselective transformations, few scaffolds stereogenic at boron and configurationally stable have been reported to date. Herein, we describe an original library of chiral NHC-boranes, stereogenic at the boron atom, that has been prepared in only a few steps and in good yields (up to 93%). Key steps involve a chlorination/a ...[more]