FGF19 subfamily members: FGF19 and FGF21.
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ABSTRACT:
SUBMITTER: Dolegowska K
PROVIDER: S-EPMC6611749 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
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FGF19 subfamily members: FGF19 and FGF21.
Dolegowska Katarzyna K Marchelek-Mysliwiec Malgorzata M Nowosiad-Magda Monika M Slawinski Michal M Dolegowska Barbara B
Journal of physiology and biochemistry 20190329 2
Fibroblast growth factors (FGF) constitute a large family of proteins with pleiotropic effects on development, organogenesis, and metabolism. The FGF19 subclass includes growth factors circulating with the blood referred to as endocrine FGF. Representatives of the FGF19 subclass, including FGF19, FGF21, and FGF23, act via FGFR receptors. The proteins of FGF19 subfamily influence the enterohepatic circulation of bile, participate in glucose and lipid metabolism regulation, and maintenance of phos ...[more]
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