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Office-based intravitreal injection of expansile gas for management of macular hole in previously vitrectomized eyes.


ABSTRACT: Purpose:To report the successful closure of full-thickness macular hole (MH), using an office-based intravitreal gas injection, in two eyes having undergone prior pars plana vitrectomy (PPV). Observations:Patient 1 presented with acute loss of visual acuity to 20/300 in the left eye 5 months following PPV for fovea-off rhegmatogenous retinal detachment; MH was confirmed by examination and optical coherence tomography (OCT). 0.6?cc of 100% C3F8 gas was injected, with subsequent MH closure following one week of face-down positioning. Patient 2 presented with right eye visual acuity of 20/60 one month following PPV for optic nerve pit-associated maculopathy; MH was confirmed by examination and OCT. 0.85?cc of 100% C3F8 gas was injected in the office, with subsequent MH closure following one week of face-down positioning. Conclusions and importance:MH management in previously vitrectomized eyes has traditionally been repeat PPV with internal limiting membrane peeling, fluid-air exchange, and expansile gas exchange. Intravitreal gas injection, in an office-based setting, is a viable clinical approach to close MH in some previously vitrectomized eyes.

SUBMITTER: Apolinario MA 

PROVIDER: S-EPMC6614528 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Office-based intravitreal injection of expansile gas for management of macular hole in previously vitrectomized eyes.

Apolinario Michael A MA   Lampen Shaun I R SIR   Wong Tien P TP   Henry Christopher R CR   Wykoff Charles C CC  

American journal of ophthalmology case reports 20190705


<h4>Purpose</h4>To report the successful closure of full-thickness macular hole (MH), using an office-based intravitreal gas injection, in two eyes having undergone prior pars plana vitrectomy (PPV).<h4>Observations</h4>Patient 1 presented with acute loss of visual acuity to 20/300 in the left eye 5 months following PPV for fovea-off rhegmatogenous retinal detachment; MH was confirmed by examination and optical coherence tomography (OCT). 0.6 cc of 100% C3F8 gas was injected, with subsequent MH  ...[more]

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