Ontology highlight
ABSTRACT:
SUBMITTER: Bomsztyk K
PROVIDER: S-EPMC6614803 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Bomsztyk Karol K Mar Daniel D Wang Yuliang Y Denisenko Oleg O Ware Carol C Frazar Christian D CD Blattler Adam A Maxwell Adam D AD MacConaghy Brian E BE Matula Thomas J TJ
Nucleic acids research 20190701 12
Chromatin immunoprecipitation (ChIP) is the most widely used approach for identification of genome-associated proteins and their modifications. We have previously introduced a microplate-based ChIP platform, Matrix ChIP, where the entire ChIP procedure is done on the same plate without sample transfers. Compared to conventional ChIP protocols, the Matrix ChIP assay is faster and has increased throughput. However, even with microplate ChIP assays, sample preparation and chromatin fragmentation (w ...[more]