Ontology highlight
ABSTRACT:
SUBMITTER: Nord H
PROVIDER: S-EPMC6615617 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Nord Hanna H Dennhag Nils N Tydinger Hanna H von Hofsten Jonas J
PloS one 20190709 7
The hepatocyte growth factor receptor C-met plays an important role in cellular migration, which is crucial for many developmental processes as well as for cancer cell metastasis. C-met has been linked to the development of mammalian appendicular muscle, which are derived from migrating muscle progenitor cells (MMPs) from within the somite. Mammalian limbs are homologous to the teleost pectoral and pelvic fins. In this study we used Crispr/Cas9 to mutate the zebrafish met gene and found that the ...[more]